Bee Venom Effective Against Diabetes, Cancer and COVID-19?
Science and Health Blog
New research published by an international team of scientists proposes the use of bee venom as a potential adjuvant against COVID-19. The authors indicate the potential of bee venom to disrupt the protective membrane envelopes or the replication of a wide variety of enveloped and non-enveloped viruses, including Human Immunodeficiency Virus (HIV), Coxsackievirus, Enterovirus, Influenza A Viruses, Human Immunodeficiency Virus (HIV), H1N1, Herpes Simplex Virus (HSV), Junín Virus (JV), Respiratory Syncytial Virus (RSV), Vesicular Stomatitis Virus (VSV) and Tobacco Mosaic Virus (TMV).
The authors point out that bee venom, in low doses and controlled dilute concentrations, triggers a range of anti-inflammatory responses, and have been deployed for management of diabetes, rheumatoid arthritis, heart disease, obesity, asthma, skin diseases, and central nervous system-associated diseases, such as Alzheimer's disease, Parkinson's disease, and sclerosis. At low doses, bee venom can suppress inflammatory cytokines such as interleukin-6 (IL-6), IL-8, interferon-γ (IFN-γ), and tumor necrosis factor-α (TNF-α).
In fact, data published in sciencedirect.com indicates that beekeepers living in the epicenter of the SARS-CoV-2 virus did not contract the virus, and neither did a group of patients receiving apitherapy. A total of 5115 beekeepers were surveyed from February 23 to March 8, 2020, including 723 in Wuhan, the outbreak epicentre of Hubei. None of these beekeepers developed symptoms associated with COVID-19, and their health was totally normal.
Bee venom is a biotoxin which can cause severe allergic reactions in some people due to the excessive stress response of the immune system. At the same time, bee venom and its main polypeptide component melttin, are linked, similar to expensive chemotherapeutic agents, to variety of cancer management effects including apoptosis, necrosis, cytotoxicity and mitochondrial disruption, inhibition of angiogenesis, metastasis and invasion of cancer cells, including prostate, breast, lung, liver and bladder.
Bee venom therapy, has also been used in traditional medicine to treat diseases such as arthritis, diabetes, rheumatism, pain, tumors, and skin diseases.
Melittin, is a non-selective cytolytic peptide which binds to negatively charged phospholipid bilayers membrane surfaces and therefore, physically and chemically disrupts all prokaryotic and eukaryotic cell membranes including our red blood cells, hence its biotoxic effect.
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